Analysis of protein adduction kinetics by quantitative mass spectrometry
نویسندگان
چکیده
منابع مشابه
Protein analysis by hydrogen exchange mass spectrometry.
Mass spectrometry has provided a powerful method for monitoring hydrogen exchange of protein backbone amides with deuterium from solvent. In comparison to popular NMR approaches, mass spectrometry has the advantages of higher sensitivity, wider coverage of sequence, and the ability to analyze larger proteins. Proteolytic fragmentation of proteins following the exchange reaction provides moderat...
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ژورنال
عنوان ژورنال: Chemico-Biological Interactions
سال: 2007
ISSN: 0009-2797
DOI: 10.1016/j.cbi.2007.03.005